3gd2

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Template:STRUCTURE 3gd2

File:3gd2.png

isoxazole ligand bound to farnesoid X receptor (FXR)isoxazole ligand bound to farnesoid X receptor (FXR)

Template:ABSTRACT PUBMED 19410460

About this StructureAbout this Structure

3gd2 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Bass JY, Caldwell RD, Caravella JA, Chen L, Creech KL, Deaton DN, Madauss KP, Marr HB, McFadyen RB, Miller AB, Parks DJ, Todd D, Williams SP, Wisely GB. Substituted isoxazole analogs of farnesoid X receptor (FXR) agonist GW4064. Bioorg Med Chem Lett. 2009 Jun 1;19(11):2969-73. Epub 2009 Apr 18. PMID:19410460 doi:10.1016/j.bmcl.2009.04.047

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