2qqk

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Template:STRUCTURE 2qqk

Neuropilin-2 a1a2b1b2 Domains in Complex with a Semaphorin-Blocking FabNeuropilin-2 a1a2b1b2 Domains in Complex with a Semaphorin-Blocking Fab

Template:ABSTRACT PUBMED 17989695

FunctionFunction

[NRP2_HUMAN] High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF.

About this StructureAbout this Structure

2qqk is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. ↑ Appleton BA, Wu P, Maloney J, Yin J, Liang WC, Stawicki S, Mortara K, Bowman KK, Elliott JM, Desmarais W, Bazan JF, Bagri A, Tessier-Lavigne M, Koch AW, Wu Y, Watts RJ, Wiesmann C. Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding. EMBO J. 2007 Nov 28;26(23):4902-12. Epub 2007 Nov 8. PMID:17989695

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