2f7z
Protein Kinase A bound to (R)-1-(1H-Indol-3-ylmethyl)-2-(2-pyridin-4-yl-[1,7]naphtyridin-5-yloxy)-ehylamineProtein Kinase A bound to (R)-1-(1H-Indol-3-ylmethyl)-2-(2-pyridin-4-yl-[1,7]naphtyridin-5-yloxy)-ehylamine
Template:ABSTRACT PUBMED 16413780
About this StructureAbout this Structure
2f7z is a 2 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Li Q, Woods KW, Thomas S, Zhu GD, Packard G, Fisher J, Li T, Gong J, Dinges J, Song X, Abrams J, Luo Y, Johnson EF, Shi Y, Liu X, Klinghofer V, Des Jong R, Oltersdorf T, Stoll VS, Jakob CG, Rosenberg SH, Giranda VL. Synthesis and structure-activity relationship of 3,4'-bispyridinylethylenes: discovery of a potent 3-isoquinolinylpyridine inhibitor of protein kinase B (PKB/Akt) for the treatment of cancer. Bioorg Med Chem Lett. 2006 Apr 1;16(7):2000-7. Epub 2006 Jan 18. PMID:16413780 doi:10.1016/j.bmcl.2005.12.065
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OCACategories:
- Pages with broken file links
- Bos taurus
- Non-specific serine/threonine protein kinase
- Abrams, J.
- Dinges, J.
- Fisher, J.
- Giranda, V L.
- Gong, J.
- Jakob, C G.
- Johnson, E F.
- Jong, R Des.
- Klinghofer, V.
- Li, Q.
- Li, T.
- Liu, X.
- Luo, Y.
- Oltersdorf, T.
- Packard, G.
- Rosenberg, S H.
- Shi, Y.
- Song, X.
- Stoll, V S.
- Thomas, S.
- Woods, K W.
- Zhu, G D.
- Akt inhibitor
- Protein kinase some
- Transferase