1ga3
NMR STRUCTURE OF INTERLEUKIN-13NMR STRUCTURE OF INTERLEUKIN-13
Template:ABSTRACT PUBMED 11419949
DiseaseDisease
[IL13_HUMAN] Defects in IL13 may be a cause of susceptibility to allergic rhinitis (ALRH) [MIM:607154]. Allergic rhinitis is a common disease of complex inheritance and is characterized by mucosal inflammation caused by allergen exposure.
FunctionFunction
[IL13_HUMAN] Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses.
About this StructureAbout this Structure
1ga3 is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Eisenmesser EZ, Horita DA, Altieri AS, Byrd RA. Solution structure of interleukin-13 and insights into receptor engagement. J Mol Biol. 2001 Jun 29;310(1):231-41. PMID:11419949 doi:http://dx.doi.org/10.1006/jmbi.2001.4765