4pm3

Structure of the double-stranded DNA binding type IV secretion protein TraN from EnterococcusStructure of the double-stranded DNA binding type IV secretion protein TraN from Enterococcus

Structural highlights 4pm3 is a 2 chain structure. This structure supersedes the now removed PDB entry 4hh7. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: , Related: 4hh7 Resources: FirstGlance, OCA, RCSB, PDBsum Publication Abstract from PubMed Conjugative plasmid transfer is the most important route for the spread of resistance and virulence genes among bacteria. Consequently, bacteria carrying conjugative plasmids are a substantial threat to human health, especially hospitalized patients. Whilst detailed information about the process has been obtained for Gram-negative type-4 secretion systems, little is known about the corresponding mechanisms in Gram-positive (G+) bacteria. The successful purification and crystallization of the putative transfer protein TraN from the G+ conjugative model plasmid pIP501 of Enterococcus faecalis are presented. Native crystals diffracted to 1.8 A resolution on a synchrotron beamline. The crystals belonged to space group P2(1), with unit-cell parameters a=32.88, b=54.94, c=57.71 A, beta=91.89 degrees and two molecules per asymmetric unit. Crystallization and first data collection of the putative transfer protein TraN from the Gram-positive conjugative plasmid pIP501.,Goessweiner-Mohr N, Fercher C, Abajy MY, Grohmann E, Keller W Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Nov 1;68(Pt 11):1402-5., doi: 10.1107/S174430911204184X. Epub 2012 Oct 30. PMID:23143259 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

spinqualitylabelsall models 4pm3, resolution 1.80Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image