4n95
E. coli sliding clamp in complex with 5-chloroindoline-2,3-dioneE. coli sliding clamp in complex with 5-chloroindoline-2,3-dione
FunctionFunction
[DPO3B_ECOLI] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA.
About this StructureAbout this Structure
4n95 is a 2 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.