4c3m
Structure of wildtype PII from S. elongatus at medium resolutionStructure of wildtype PII from S. elongatus at medium resolution
FunctionFunction
[GLNB_SYNE7] P-II indirectly controls the transcription of the GS gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA. When P-II is phosphorylated, these events are reversed. In nitrogen-limiting conditions, when the ratio of Gln to 2-ketoglutarate decreases, P-II is phosphorylated which allows the deadenylation of glutamine synthetase (GS), thus activating the enzyme.
About this StructureAbout this Structure
4c3m is a 3 chain structure. Full crystallographic information is available from OCA.