1e9c
MUTANT HUMAN THYMIDYLATE KINASE COMPLEXED WITH TMP AND APPNPMUTANT HUMAN THYMIDYLATE KINASE COMPLEXED WITH TMP AND APPNP
About this StructureAbout this Structure
1e9c is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Ostermann N, Lavie A, Padiyar S, Brundiers R, Veit T, Reinstein J, Goody RS, Konrad M, Schlichting I. Potentiating AZT activation: structures of wild-type and mutant human thymidylate kinase suggest reasons for the mutants' improved kinetics with the HIV prodrug metabolite AZTMP. J Mol Biol. 2000 Nov 17;304(1):43-53. PMID:11071809 doi:10.1006/jmbi.2000.4175