1vz0
CHROMOSOME SEGREGATION PROTEIN SPO0J FROM THERMUS THERMOPHILUS
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OverviewOverview
Prokaryotic chromosomes and plasmids encode partitioning systems that are, required for DNA segregation at cell division. The plasmid partitioning, loci encode two proteins, ParA and ParB, and a cis-acting centromere-like, site denoted parS. The chromosomally encoded homologues of ParA and ParB, Soj and Spo0J, play an active role in chromosome segregation during, bacterial cell division and sporulation. Spo0J is a DNA-binding protein, that binds to parS sites in vivo. We have solved the X-ray crystal, structure of a C-terminally truncated Spo0J (amino acids 1-222) from, Thermus thermophilus to 2.3 A resolution by multiwavelength anomalous, dispersion. It is a DNA-binding protein with structural similarity to the, helix-turn-helix (HTH) motif of the lambda repressor DNA-binding domain., ... [(full description)]
About this StructureAbout this Structure
1VZ0 is a [Single protein] structure of sequence from [Thermus thermophilus] with CO and MG as [ligands]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
ReferenceReference
Structural analysis of the chromosome segregation protein Spo0J from Thermus thermophilus., Leonard TA, Butler PJ, Lowe J, Mol Microbiol. 2004 Jul;53(2):419-32. PMID:15228524
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