3o2d
Crystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibodyCrystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibody
Template:ABSTRACT PUBMED 21134642
FunctionFunction
[CD4_HUMAN] Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.
About this StructureAbout this Structure
3o2d is a 3 chain structure with sequence from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Freeman MM, Seaman MS, Rits-Volloch S, Hong X, Kao CY, Ho DD, Chen B. Crystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibody. Structure. 2010 Dec 8;18(12):1632-41. PMID:21134642 doi:10.1016/j.str.2010.09.017