3knx
HCV NS3 protease domain with P1-P3 macrocyclic ketoamide inhibitorHCV NS3 protease domain with P1-P3 macrocyclic ketoamide inhibitor
Template:ABSTRACT PUBMED 19102654
About this StructureAbout this Structure
3KNX is a 4 chains structure with sequences from Hepatitis c virus subtype 1a. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Venkatraman S, Velazquez F, Wu W, Blackman M, Chen KX, Bogen S, Nair L, Tong X, Chase R, Hart A, Agrawal S, Pichardo J, Prongay A, Cheng KC, Girijavallabhan V, Piwinski J, Shih NY, Njoroge FG. Discovery and structure-activity relationship of P1-P3 ketoamide derived macrocyclic inhibitors of hepatitis C virus NS3 protease. J Med Chem. 2009 Jan 22;52(2):336-46. PMID:19102654 doi:10.1021/jm800940u
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OCACategories:
- Pages with broken file links
- Hepatitis c virus subtype 1a
- Agrawal, S.
- Blackman, M.
- Bogen, S.
- Chase, R.
- Chen, K X.
- Cheng, K C.
- Girijavallabhan, V.
- Hart, A.
- Nair, L.
- Njoroge, F G.
- Pichardo, J.
- Piwinski, J.
- Prongay, A.
- Shih, N Y.
- Tong, X.
- Velazquez, F.
- Venkatraman, S.
- Wu, W.
- Atp-binding
- Envelope protein
- Helicase
- Hepatitis c virus
- Hydrolase
- Macrocyclic ketoamide inhibitor
- Membrane
- Ns3 protease domain
- Nucleotide-binding
- Rna replication
- Serine protease
- Transmembrane
- Viral protein