3jpv
Crystal structure of human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and a pyrrolo[2,3-a]carbazole ligandCrystal structure of human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and a pyrrolo[2,3-a]carbazole ligand
Template:ABSTRACT PUBMED 19788246
About this StructureAbout this Structure
3JPV is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Akue-Gedu R, Rossignol E, Azzaro S, Knapp S, Filippakopoulos P, Bullock AN, Bain J, Cohen P, Prudhomme M, Anizon F, Moreau P. Synthesis, kinase inhibitory potencies, and in vitro antiproliferative evaluation of new Pim kinase inhibitors. J Med Chem. 2009 Oct 22;52(20):6369-81. PMID:19788246 doi:10.1021/jm901018f
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OCACategories:
- Pages with broken file links
- Homo sapiens
- Non-specific serine/threonine protein kinase
- Akue-Gedu, R.
- Amizon, F.
- Arrowsmith, C H.
- Azzaro, S.
- Bain, J.
- Bountra, C.
- Bullock, A N.
- Cohen, P.
- Delft, F von.
- Edwards, A.
- Fedorov, O.
- Filippakopoulos, P.
- Knapp, S.
- Moreau, P.
- Prudhomme, M.
- Rossignol, E.
- SGC, Structural Genomics Consortium.
- Weigelt, J.
- Alternative initiation
- Atp-binding
- Cell membrane
- Cytoplasm
- Kinase
- Manganese
- Membrane
- Metal-binding
- Nucleotide-binding
- Nucleus
- Oncogene
- Phosphoprotein
- Pim1
- Polymorphism
- Proto-oncogene
- Serine-threonine
- Serine/threonine-protein kinase
- Sgc
- Structural genomics consortium
- Transferase
- Transferase / transferase inhibitor complex