2q2y
Crystal Structure of KSP in complex with Inhibitor 1Crystal Structure of KSP in complex with Inhibitor 1
About this StructureAbout this Structure
2q2y is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
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ReferenceReference
- ↑ Roecker AJ, Coleman PJ, Mercer SP, Schreier JD, Buser CA, Walsh ES, Hamilton K, Lobell RB, Tao W, Diehl RE, South VJ, Davide JP, Kohl NE, Yan Y, Kuo LC, Li C, Fernandez-Metzler C, Mahan EA, Prueksaritanont T, Hartman GD. Kinesin spindle protein (KSP) inhibitors. Part 8: Design and synthesis of 1,4-diaryl-4,5-dihydropyrazoles as potent inhibitors of the mitotic kinesin KSP. Bioorg Med Chem Lett. 2007 Oct 15;17(20):5677-82. Epub 2007 Aug 21. PMID:17766111 doi:10.1016/j.bmcl.2007.07.074