2hh0
Structure of an Anti-PrP Fab, P-Clone, in Complex with its Cognate Bovine Peptide Epitope.Structure of an Anti-PrP Fab, P-Clone, in Complex with its Cognate Bovine Peptide Epitope.
About this StructureAbout this Structure
2hh0 is a 3 chain structure with sequence from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Luginbuhl B, Kanyo Z, Jones RM, Fletterick RJ, Prusiner SB, Cohen FE, Williamson RA, Burton DR, Pluckthun A. Directed evolution of an anti-prion protein scFv fragment to an affinity of 1 pM and its structural interpretation. J Mol Biol. 2006 Oct 13;363(1):75-97. Epub 2006 Jul 21. PMID:16962610 doi:10.1016/j.jmb.2006.07.027
- ↑ Safar JG, Scott M, Monaghan J, Deering C, Didorenko S, Vergara J, Ball H, Legname G, Leclerc E, Solforosi L, Serban H, Groth D, Burton DR, Prusiner SB, Williamson RA. Measuring prions causing bovine spongiform encephalopathy or chronic wasting disease by immunoassays and transgenic mice. Nat Biotechnol. 2002 Nov;20(11):1147-50. Epub 2002 Oct 21. PMID:12389035 doi:10.1038/nbt748