Template:STRUCTURE 3nee

File:3nee.png

Wild type human transthyretin (TTR) complexed with GC-1 (TTRwt:GC-1)Wild type human transthyretin (TTR) complexed with GC-1 (TTRwt:GC-1)

Template:ABSTRACT PUBMED 20937391

About this StructureAbout this Structure

3nee is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1][xtra 2]

  1. Trivella DB, Sairre MI, Foguel D, Lima LM, Polikarpov I. The binding of synthetic triiodo l-thyronine analogs to human transthyretin: Molecular basis of cooperative and non-cooperative ligand recognition. J Struct Biol. 2010 Oct 16. PMID:20937391 doi:10.1016/j.jsb.2010.10.003
  2. Trivella DB, Bleicher L, Palmieri Lde C, Wiggers HJ, Montanari CA, Kelly JW, Lima LM, Foguel D, Polikarpov I. Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding. J Struct Biol. 2010 Jun;170(3):522-31. Epub 2010 Mar 6. PMID:20211733 doi:10.1016/j.jsb.2010.03.002

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