3cqu

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Template:STRUCTURE 3cqu

File:3cqu.png

Crystal Structure of Akt-1 complexed with substrate peptide and inhibitorCrystal Structure of Akt-1 complexed with substrate peptide and inhibitor

Template:ABSTRACT PUBMED 18456494

About this StructureAbout this Structure

3CQU is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

^{[xtra 1]}

↑ Lippa B, Pan G, Corbett M, Li C, Kauffman GS, Pandit J, Robinson S, Wei L, Kozina E, Marr ES, Borzillo G, Knauth E, Barbacci-Tobin EG, Vincent P, Troutman M, Baker D, Rajamohan F, Kakar S, Clark T, Morris J. Synthesis and structure based optimization of novel Akt inhibitors. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3359-63. Epub 2008 Apr 15. PMID:18456494 doi:10.1016/j.bmcl.2008.04.034

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OCA

[1] Lippa B, Pan G, Corbett M, Li C, Kauffman GS, Pandit J, Robinson S, Wei L, Kozina E, Marr ES, Borzillo G, Knauth E, Barbacci-Tobin EG, Vincent P, Troutman M, Baker D, Rajamohan F, Kakar S, Clark T, Morris J. Synthesis and structure based optimization of novel Akt inhibitors. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3359-63. Epub 2008 Apr 15. PMID:18456494 doi:10.1016/j.bmcl.2008.04.034

[xtra 1]