2gv7

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Template:STRUCTURE 2gv7

File:2gv7.png

Structure of Matriptase in Complex with Inhibitor CJ-672Structure of Matriptase in Complex with Inhibitor CJ-672

Template:ABSTRACT PUBMED 16821772

DiseaseDisease

Known disease associated with this structure: Ichthyosis with hypotrichosis OMIM:[606797]

About this StructureAbout this Structure

2GV7 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

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↑ Steinmetzer T, Schweinitz A, Sturzebecher A, Donnecke D, Uhland K, Schuster O, Steinmetzer P, Muller F, Friedrich R, Than ME, Bode W, Sturzebecher J. Secondary amides of sulfonylated 3-amidinophenylalanine. New potent and selective inhibitors of matriptase. J Med Chem. 2006 Jul 13;49(14):4116-26. PMID:16821772 doi:10.1021/jm051272l

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OCA

[1] Steinmetzer T, Schweinitz A, Sturzebecher A, Donnecke D, Uhland K, Schuster O, Steinmetzer P, Muller F, Friedrich R, Than ME, Bode W, Sturzebecher J. Secondary amides of sulfonylated 3-amidinophenylalanine. New potent and selective inhibitors of matriptase. J Med Chem. 2006 Jul 13;49(14):4116-26. PMID:16821772 doi:10.1021/jm051272l

[xtra 1]