Lambda repressor
IntroductionIntroduction
cI is a transcription inhibitor of bacteriophage Lambda. Also known as Lambda Repressor, cI is responsible for maintaining the lysogenic life cycle of phage Lambda. This is achieved when two repressor dimers bind cooperatively to adjacent operator sites on the DNA. The cooperative binding induces repression of the cro gene and simultaneous activation of the cI gene, which code for proteins Cro and cI, respectively.
Structural OverviewStructural Overview
The Lambda Repressor dimer is composed of two identical polypeptide chains of 236 amino acid residues each.
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