3fl5
Protein kinase CK2 in complex with the inhibitor QuinalizarinProtein kinase CK2 in complex with the inhibitor Quinalizarin
Template:ABSTRACT PUBMED 19432557
About this StructureAbout this Structure
3fl5 is a 1 chain structure of Casein kinase with sequence from Zea mays. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Cozza G, Mazzorana M, Papinutto E, Bain J, Elliott M, di Maira G, Gianoncelli A, Pagano MA, Sarno S, Ruzzene M, Battistutta R, Meggio F, Moro S, Zagotto G, Pinna LA. Quinalizarin as a potent, selective and cell-permeable inhibitor of protein kinase CK2. Biochem J. 2009 Jul 15;421(3):387-95. PMID:19432557 doi:10.1042/BJ20090069
- ↑ Raaf J, Klopffleisch K, Issinger OG, Niefind K. The catalytic subunit of human protein kinase CK2 structurally deviates from its maize homologue in complex with the nucleotide competitive inhibitor emodin. J Mol Biol. 2008 Mar 14;377(1):1-8. Epub 2008 Jan 11. PMID:18242640 doi:http://dx.doi.org/10.1016/j.jmb.2008.01.008
- ↑ Battistutta R, Sarno S, De Moliner E, Papinutto E, Zanotti G, Pinna LA. The replacement of ATP by the competitive inhibitor emodin induces conformational modifications in the catalytic site of protein kinase CK2. J Biol Chem. 2000 Sep 22;275(38):29618-22. PMID:10882732 doi:10.1074/jbc.M004257200