2oic

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File:2oic.png

Template:STRUCTURE 2oic

Crystal structure of IRAK4 kinase domain complexed with staurosporineCrystal structure of IRAK4 kinase domain complexed with staurosporine

Template:ABSTRACT PUBMED 17312103

DiseaseDisease

Known disease associated with this structure: IRAK4 deficiency OMIM:[606883], Invasive pneumococcal disease, recurrent isolated, 1 OMIM:[606883]

About this StructureAbout this Structure

2OIC is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Kuglstatter A, Villasenor AG, Shaw D, Lee SW, Tsing S, Niu L, Song KW, Barnett JW, Browner MF. Cutting Edge: IL-1 receptor-associated kinase 4 structures reveal novel features and multiple conformations. J Immunol. 2007 Mar 1;178(5):2641-5. PMID:17312103

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