1gpu
TRANSKETOLASE COMPLEX WITH REACTION INTERMEDIATETRANSKETOLASE COMPLEX WITH REACTION INTERMEDIATE
About this StructureAbout this Structure
1gpu is a 2 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.
ReferenceReference
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- ↑ Fiedler E, Thorell S, Sandalova T, Golbik R, Konig S, Schneider G. Snapshot of a key intermediate in enzymatic thiamin catalysis: crystal structure of the alpha-carbanion of (alpha,beta-dihydroxyethyl)-thiamin diphosphate in the active site of transketolase from Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 2002 Jan 22;99(2):591-5. Epub 2002 Jan 2. PMID:11773632 doi:10.1073/pnas.022510999
- ↑ Wikner C, Nilsson U, Meshalkina L, Udekwu C, Lindqvist Y, Schneider G. Identification of catalytically important residues in yeast transketolase. Biochemistry. 1997 Dec 16;36(50):15643-9. PMID:9398292 doi:10.1021/bi971606b
- ↑ Meshalkina L, Nilsson U, Wikner C, Kostikowa T, Schneider G. Examination of the thiamin diphosphate binding site in yeast transketolase by site-directed mutagenesis. Eur J Biochem. 1997 Mar 1;244(2):646-52. PMID:9119035
- ↑ Kern D, Kern G, Neef H, Tittmann K, Killenberg-Jabs M, Wikner C, Schneider G, Hubner G. How thiamine diphosphate is activated in enzymes. Science. 1997 Jan 3;275(5296):67-70. PMID:8974393
- ↑ Nikkola M, Lindqvist Y, Schneider G. Refined structure of transketolase from Saccharomyces cerevisiae at 2.0 A resolution. J Mol Biol. 1994 May 6;238(3):387-404. PMID:8176731 doi:http://dx.doi.org/10.1006/jmbi.1994.1299