Template:STRUCTURE 2as5

File:2as5.png

Structure of the DNA binding domains of NFAT and FOXP2 bound specifically to DNA.Structure of the DNA binding domains of NFAT and FOXP2 bound specifically to DNA.

Template:ABSTRACT PUBMED 16873067

DiseaseDisease

Known disease associated with this structure: Speech-language disorder-1 OMIM:[605317]

About this StructureAbout this Structure

2AS5 is a 8 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Wu Y, Borde M, Heissmeyer V, Feuerer M, Lapan AD, Stroud JC, Bates DL, Guo L, Han A, Ziegler SF, Mathis D, Benoist C, Chen L, Rao A. FOXP3 controls regulatory T cell function through cooperation with NFAT. Cell. 2006 Jul 28;126(2):375-87. PMID:16873067 doi:10.1016/j.cell.2006.05.042

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