3gnv

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File:3gnv.jpg

Template:STRUCTURE 3gnv

HCV NS5B polymerase in complex with 1,5 benzodiazepine inhibitor 1bHCV NS5B polymerase in complex with 1,5 benzodiazepine inhibitor 1b

Template:ABSTRACT PUBMED 19507864

About this StructureAbout this Structure

3GNV is a 2 chains structure of sequences from Viruses. Full crystallographic information is available from OCA.

ReferenceReference

^{[xtra 1]}

↑ Vandyck K, Cummings MD, Nyanguile O, Boutton CW, Vendeville S, McGowan D, Devogelaere B, Amssoms K, Last S, Rombauts K, Tahri A, Lory P, Hu L, Beauchamp DA, Simmen K, Raboisson P. Structure-based design of a benzodiazepine scaffold yields a potent allosteric inhibitor of hepatitis C NS5B RNA polymerase. J Med Chem. 2009 Jul 23;52(14):4099-102. PMID:19507864 doi:10.1021/jm9005548

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OCA

[1] Vandyck K, Cummings MD, Nyanguile O, Boutton CW, Vendeville S, McGowan D, Devogelaere B, Amssoms K, Last S, Rombauts K, Tahri A, Lory P, Hu L, Beauchamp DA, Simmen K, Raboisson P. Structure-based design of a benzodiazepine scaffold yields a potent allosteric inhibitor of hepatitis C NS5B RNA polymerase. J Med Chem. 2009 Jul 23;52(14):4099-102. PMID:19507864 doi:10.1021/jm9005548

[xtra 1]