1owj
Substituted 2-Naphthamidine Inhibitors of UrokinaseSubstituted 2-Naphthamidine Inhibitors of Urokinase
Template:ABSTRACT PUBMED 14711304
DiseaseDisease
Known disease associated with this structure: Alzheimer disease, late-onset, susceptibility to OMIM:[191840]
About this StructureAbout this Structure
1OWJ is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Wendt MD, Rockway TW, Geyer A, McClellan W, Weitzberg M, Zhao X, Mantei R, Nienaber VL, Stewart K, Klinghofer V, Giranda VL. Identification of novel binding interactions in the development of potent, selective 2-naphthamidine inhibitors of urokinase. Synthesis, structural analysis, and SAR of N-phenyl amide 6-substitution. J Med Chem. 2004 Jan 15;47(2):303-24. PMID:14711304 doi:10.1021/jm0300072
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