2ghm

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Template:STRUCTURE 2ghm

File:2ghm.png

Mutated MAP kinase P38 (Mus Musculus) in complex with Inhbitor PG-895449Mutated MAP kinase P38 (Mus Musculus) in complex with Inhbitor PG-895449

Template:ABSTRACT PUBMED 16632356

About this StructureAbout this Structure

2GHM is a 1 chain structure of sequence from Mus musculus. Full crystallographic information is available from OCA.

ReferenceReference

^{[xtra 1]}

↑ Brugel TA, Maier JA, Clark MP, Sabat M, Golebiowski A, Bookland RG, Laufersweiler MJ, Laughlin SK, Vanrens JC, De B, Hsieh LC, Mekel MJ, Janusz MJ. Development of N-2,4-pyrimidine-N-phenyl-N'-phenyl ureas as inhibitors of tumor necrosis factor alpha (TNF-alpha) synthesis. Part 1. Bioorg Med Chem Lett. 2006 Jul 1;16(13):3510-3. Epub 2006 May 2. PMID:16632356 doi:10.1016/j.bmcl.2006.03.095

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OCA

[1] Brugel TA, Maier JA, Clark MP, Sabat M, Golebiowski A, Bookland RG, Laufersweiler MJ, Laughlin SK, Vanrens JC, De B, Hsieh LC, Mekel MJ, Janusz MJ. Development of N-2,4-pyrimidine-N-phenyl-N'-phenyl ureas as inhibitors of tumor necrosis factor alpha (TNF-alpha) synthesis. Part 1. Bioorg Med Chem Lett. 2006 Jul 1;16(13):3510-3. Epub 2006 May 2. PMID:16632356 doi:10.1016/j.bmcl.2006.03.095

[xtra 1]