1adv
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EARLY E2A DNA-BINDING PROTEIN
OverviewOverview
A second crystal form of the C-terminal domain of the adenovirus, single-stranded DNA binding protein crystallizes in space group, P2(1)2(1)2(1) with a=61.0 angstrom, b=91.2 angstrom and c=149.4 angstrom., The crystals contain two molecules per asymmetric unit and diffract to a, maximum resolution of 3.0 angstrom. The crystal is composed of infinite, chains of molecules along the crystallographic 2(1) axis parallel to c., The principal intermolecular interaction is a hooking of the C-terminal 17, residues of one molecule onto the next molecule in the protein chain., Adjacent molecules in the chain are rotated approximately 90 degrees with, respect to their neighbours. The difference in relative orientation of, adjacent molecules between the two crystal forms of the protein implies a, degree of flexibility in the protein chain that would facilitate DNA, binding.
About this StructureAbout this Structure
1ADV is a Single protein structure of sequence from Human adenovirus 11 with ZN as ligand. Full crystallographic information is available from OCA.
ReferenceReference
Alternative arrangements of the protein chain are possible for the adenovirus single-stranded DNA binding protein., Kanellopoulos PN, Tsernoglou D, van der Vliet PC, Tucker PA, J Mol Biol. 1996 Mar 22;257(1):1-8. PMID:8632448
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