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3fxi

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Template:STRUCTURE 3fxi

File:3fxi.png

Crystal structure of the human TLR4-human MD-2-E.coli LPS Ra complexCrystal structure of the human TLR4-human MD-2-E.coli LPS Ra complex

Template:ABSTRACT PUBMED 19252480

About this StructureAbout this Structure

3fxi is a 4 chain structure of Toll-like Receptors with sequence from Escherichia coli and Homo sapiens. The November 2011 RCSB PDB Molecule of the Month feature on Toll-like Receptors by David Goodsell is 10.2210/rcsb_pdb/mom_2011_11. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1][xtra 2]

  1. ↑ Park BS, Song DH, Kim HM, Choi BS, Lee H, Lee JO. The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex. Nature. 2009 Apr 30;458(7242):1191-5. Epub 2009 Mar 1. PMID:19252480 doi:10.1038/nature07830
  2. ↑ Lin SC, Lo YC, Wu H. Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling. Nature. 2010 Jun 17;465(7300):885-90. Epub 2010 May 19. PMID:20485341 doi:10.1038/nature09121

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