1oiq
IMIDAZOPYRIDINES: A POTENT AND SELECTIVE CLASS OF CYCLIN-DEPENDENT KINASE INHIBITORS IDENTIFIED THROUGH STRUCTURE-BASED HYBRIDISATIONIMIDAZOPYRIDINES: A POTENT AND SELECTIVE CLASS OF CYCLIN-DEPENDENT KINASE INHIBITORS IDENTIFIED THROUGH STRUCTURE-BASED HYBRIDISATION
Template:ABSTRACT PUBMED 12941325
About this StructureAbout this Structure
1oiq is a 1 chain structure of Cell Division Protein Kinase 2 with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Anderson M, Beattie JF, Breault GA, Breed J, Byth KF, Culshaw JD, Ellston RP, Green S, Minshull CA, Norman RA, Pauptit RA, Stanway J, Thomas AP, Jewsbury PJ. Imidazo[1,2-a]pyridines: a potent and selective class of cyclin-dependent kinase inhibitors identified through structure-based hybridisation. Bioorg Med Chem Lett. 2003 Sep 15;13(18):3021-6. PMID:12941325
- ↑ Schulze-Gahmen U, De Bondt HL, Kim SH. High-resolution crystal structures of human cyclin-dependent kinase 2 with and without ATP: bound waters and natural ligand as guides for inhibitor design. J Med Chem. 1996 Nov 8;39(23):4540-6. PMID:8917641 doi:10.1021/jm960402a
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OCACategories:
- Pages with broken file links
- Homo sapiens
- Non-specific serine/threonine protein kinase
- Beattie, J F.
- Breault, G A.
- Byth, K F.
- Culshaw, J D.
- Ellston, R P.A.
- Green, S.
- Jewsbury, P J.
- Minshull, C A.
- Norman, R A.
- Pauptit, R A.
- Thomas, A P.
- Atp-binding
- Cell cycle
- Cell division
- Kinase
- Mitosis
- Phosphorylation
- Protein kinase
- Serine/threonine-protein kinase
- Transferase