1pv8

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File:1pv8.png

Template:STRUCTURE 1pv8

Crystal structure of a low activity F12L mutant of human phorphobilinogen synthaseCrystal structure of a low activity F12L mutant of human phorphobilinogen synthase

Template:ABSTRACT PUBMED 12897770

DiseaseDisease

Known disease associated with this structure: Porphyria, acute hepatic OMIM:[125270], Lead poisoning, susceptibility to OMIM:[125270]

About this StructureAbout this Structure

1PV8 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Breinig S, Kervinen J, Stith L, Wasson AS, Fairman R, Wlodawer A, Zdanov A, Jaffe EK. Control of tetrapyrrole biosynthesis by alternate quaternary forms of porphobilinogen synthase. Nat Struct Biol. 2003 Sep;10(9):757-63. Epub 2003 Aug 3. PMID:12897770 doi:10.1038/nsb963

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