User:Daniel Seeman/DELETE

spinqualitylabelsall models Toggle between active site inhibitor bound and allosterically inhibited caspase-7 Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

Forms of Caspase-7Forms of Caspase-7

• , trapping protein in active/substrate bound conformation.
• trapping protein in a form incompatible with substrate binding.

Molecular Playground banner: Conformational Dynamics between active and allosterically inhibited caspase-7 elucidate the mechanism of allostery in this important class of cysteine proteases.