Prolyl Endopeptidase

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Prolyl endopeptidase of Sphingomonas capsulata

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Prolyl endopeptidases (PEPs) are a class of serine proteases known to have a role in the degradation of neuropeptides and peptide hormones. PEPs are large enzymes (75kDa) that cleave after proline residues in the peptide chain.

StructureStructure

FunctionFunction

Binding MechanismBinding Mechanism

InhibitionInhibition

Pharmaceutical PossibilitiesPharmaceutical Possibilities

Celiac DiseaseCeliac Disease

Neurological DisordersNeurological Disorders

ReferencesReferences

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Andrea Gorrell, Stacey Shantz, David Canner, Michal Harel, Alexander Berchansky, Joel L. Sussman