Tetherin

Tetherin is a membrane-associated protein that may prevent the release of enveloped viruses from their host cellsTetherin is a membrane-associated protein that may prevent the release of enveloped viruses from their host cells

Replace the PDB id (use lowercase!) after the STRUCTURE_ and after PDB= to load and display another structure.

Ligands:

, ,

Gene:

TM1419, TM_1419 (Thermotoga maritima MSB8)

Activity:

Inositol-3-phosphate synthase, with EC number 5.5.1.4

Structural annotation:
Resources:	CATH : 3Cina01, 3Cina02 InterPro : Ipr016040, Ipr013021, Ipr002587 Pfam : PF07994

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, RCSB, PDBsum, TOPSAN

Coordinates:

save as pdb, mmCIF, xml

Sakuma, Noda, Urata, Kawaoka, & Yasuda (2009). Inhibition of Lassa and Marburg Virus Production by Tetherin. Journal of Virology. 83:2382-2385.

Neil, Zang, & Beiniasz (2008). Tetherin inhibits retroviral release and is antagonized by HIV-1 Vpu. Nature. 451: 425-430.