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FIBRINFIBRIN
This protein works in the blood to quickly blocks any damage to the circulatory system,
creating a temporary patch that allows time for more permanent repairs. It is a strong protein that is inactive until activated when a cut or lacerition to the skin is present. Fibrin is involved in the following biological processes of humans: Signal transduction, Blood coagulation, Platelet activation, and Protein polymerization .
FUNCTION & StructureFUNCTION & Structure
Fibrin in the blood works along with two other molecules. These molecules are platelets (small fragments of blood cells that circulate in the blood), and neighboring blood vessels which constrict when needed. These methods work together along with Fibrin to create scabs which stop the flow of blood. The structure of Fibrin is mainly consists of single alpha helices shown in pink and beta sheets shown in yellow. The of The Fibrin Protein allows it to be flexible and clog lacerations to the skin. Apart of Fibrin, there is a vertebrate hexamer containing two sets of three different chains (α, β, and γ), linked to each other by bonds.
File:Http://en.wikipedia.org/wiki/File:Fibrinandligand.pngThe image at the left is a crystal structure of the double-d fragment from human fibrin with two bound ligands. The two blue structures are the bound ligands. The chemical structures of the ligands are Ca+2 ion, alpha-D-mannose (C6H1206), and D-glcosamine (C8H15NO6).
