3b3n
Structure of neuronal NOS heme domain in complex with a inhibitor (+-)-N1-{cis-4'-[(6"-aminopyridin-2"-yl)methyl]pyrrolidin-3'-yl}ethane-1,2-diamine
About this StructureAbout this Structure
3b3n is a 2 chain structure of Nitric Oxide Synthase with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
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ReferenceReference
- ↑ Ji H, Stanton BZ, Igarashi J, Li H, Martasek P, Roman LJ, Poulos TL, Silverman RB. Minimal pharmacophoric elements and fragment hopping, an approach directed at molecular diversity and isozyme selectivity. Design of selective neuronal nitric oxide synthase inhibitors. J Am Chem Soc. 2008 Mar 26;130(12):3900-14. Epub 2008 Mar 6. PMID:18321097 doi:10.1021/ja0772041