Template:STRUCTURE 1oo5

File:1oo5.png

Studies on the Nitroreductase Prodrug-Activating System. Crystal Structures of the Enzyme Active Form and Complexes with the Inhibitor Dicoumarol and Dinitrobenzamide ProdrugsStudies on the Nitroreductase Prodrug-Activating System. Crystal Structures of the Enzyme Active Form and Complexes with the Inhibitor Dicoumarol and Dinitrobenzamide Prodrugs

Template:ABSTRACT PUBMED 12954054

About this StructureAbout this Structure

1oo5 is a 2 chain structure of Nitroreductase with sequence from Escherichia coli. Full crystallographic information is available from OCA.

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ReferenceReference

[xtra 1]

  1. Johansson E, Parkinson GN, Denny WA, Neidle S. Studies on the nitroreductase prodrug-activating system. Crystal structures of complexes with the inhibitor dicoumarol and dinitrobenzamide prodrugs and of the enzyme active form. J Med Chem. 2003 Sep 11;46(19):4009-20. PMID:12954054 doi:http://dx.doi.org/10.1021/jm030843b

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