Template:STRUCTURE 3ela

File:3ela.png

Crystal structure of active site inhibited coagulation factor VIIA mutant in complex with soluble tissue factorCrystal structure of active site inhibited coagulation factor VIIA mutant in complex with soluble tissue factor

Template:ABSTRACT PUBMED 18640965

DiseaseDisease

Known disease associated with this structure: Factor VII deficiency OMIM:[227500], Myocardial infarction, decreased susceptibility to OMIM:[227500]

About this StructureAbout this Structure

3ELA is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Bjelke JR, Olsen OH, Fodje M, Svensson LA, Bang S, Bolt G, Kragelund BB, Persson E. Mechanism of the Ca2+-induced enhancement of the intrinsic factor VIIa activity. J Biol Chem. 2008 Sep 19;283(38):25863-70. Epub 2008 Jul 17. PMID:18640965 doi:10.1074/jbc.M800841200

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