2zn7

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Template:STRUCTURE 2zn7

File:2zn7.png

CRYSTAL STRUCTURES OF PTP1B-Inhibitor ComplexesCRYSTAL STRUCTURES OF PTP1B-Inhibitor Complexes

DiseaseDisease

Known disease associated with this structure: Abdominal body fat distribution, modifier of OMIM:[176885], Insulin resistance, susceptibility to OMIM:[176885]

About this StructureAbout this Structure

2ZN7 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

Structure-based optimization of protein tyrosine phosphatase-1 B inhibitors: capturing interactions with arginine 24., Wan ZK, Lee J, Hotchandani R, Moretto A, Binnun E, Wilson DP, Kirincich SJ, Follows BC, Ipek M, Xu W, Joseph-McCarthy D, Zhang YL, Tam M, Erbe DV, Tobin JF, Li W, Tam SY, Mansour TS, Wu J, ChemMedChem. 2008 Oct;3(10):1525-9. PMID:18798205

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