1nvw

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Template:STRUCTURE 1nvw

File:1nvw.png

Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOSStructural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS

Template:ABSTRACT PUBMED 12628188

DiseaseDisease

Known disease associated with this structure: Fibromatosis, gingival OMIM:[182530], Noonan syndrome 4 OMIM:[182530]

About this StructureAbout this Structure

1NVW is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

^{[xtra 1]}

↑ Margarit SM, Sondermann H, Hall BE, Nagar B, Hoelz A, Pirruccello M, Bar-Sagi D, Kuriyan J. Structural evidence for feedback activation by Ras.GTP of the Ras-specific nucleotide exchange factor SOS. Cell. 2003 Mar 7;112(5):685-95. PMID:12628188

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OCA

[1] Margarit SM, Sondermann H, Hall BE, Nagar B, Hoelz A, Pirruccello M, Bar-Sagi D, Kuriyan J. Structural evidence for feedback activation by Ras.GTP of the Ras-specific nucleotide exchange factor SOS. Cell. 2003 Mar 7;112(5):685-95. PMID:12628188

[xtra 1]