2nzi

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Template:STRUCTURE 2nzi

File:2nzi.png

Crystal structure of domains A168-A170 from titinCrystal structure of domains A168-A170 from titin

Template:ABSTRACT PUBMED 17215480

DiseaseDisease

Known disease associated with this structure: Cardiomyopathy, dilated, 1G OMIM:[188840], Cardiomyopathy, familial hypertrophic OMIM:[188840], Muscular dystrophy, limb-girdle, type 2J OMIM:[188840], Myopathy, early-onset, with fatal cardiomyopathy OMIM:[188840], Myopathy, proximal, with early respiratory muscle involvement OMIM:[188840], Tibial muscular dystrophy, tardive OMIM:[188840]

About this StructureAbout this Structure

2NZI is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

^{[xtra 1]}

↑ Mrosek M, Labeit D, Witt S, Heerklotz H, von Castelmur E, Labeit S, Mayans O. Molecular determinants for the recruitment of the ubiquitin-ligase MuRF-1 onto M-line titin. FASEB J. 2007 May;21(7):1383-92. Epub 2007 Jan 10. PMID:17215480 doi:10.1096/fj.06-7644com

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OCA

[1] Mrosek M, Labeit D, Witt S, Heerklotz H, von Castelmur E, Labeit S, Mayans O. Molecular determinants for the recruitment of the ubiquitin-ligase MuRF-1 onto M-line titin. FASEB J. 2007 May;21(7):1383-92. Epub 2007 Jan 10. PMID:17215480 doi:10.1096/fj.06-7644com

[xtra 1]