2as5
Structure of the DNA binding domains of NFAT and FOXP2 bound specifically to DNA.Structure of the DNA binding domains of NFAT and FOXP2 bound specifically to DNA.
DiseaseDisease
Known disease associated with this structure: Speech-language disorder-1 OMIM:[605317]
About this StructureAbout this Structure
2AS5 is a 8 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Wu Y, Borde M, Heissmeyer V, Feuerer M, Lapan AD, Stroud JC, Bates DL, Guo L, Han A, Ziegler SF, Mathis D, Benoist C, Chen L, Rao A. FOXP3 controls regulatory T cell function through cooperation with NFAT. Cell. 2006 Jul 28;126(2):375-87. PMID:16873067 doi:10.1016/j.cell.2006.05.042
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