3cst

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File:3cst.png

Template:STRUCTURE 3cst

Crystal structure of PI3K p110gamma catalytical domain in complex with organoruthenium inhibitor E5E2Crystal structure of PI3K p110gamma catalytical domain in complex with organoruthenium inhibitor E5E2

Template:ABSTRACT PUBMED 18484710

About this StructureAbout this Structure

3CST is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

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↑ Xie P, Williams DS, Atilla-Gokcumen GE, Milk L, Xiao M, Smalley KS, Herlyn M, Meggers E, Marmorstein R. Structure-based design of an organoruthenium phosphatidyl-inositol-3-kinase inhibitor reveals a switch governing lipid kinase potency and selectivity. ACS Chem Biol. 2008 May 16;3(5):305-16. PMID:18484710 doi:http://dx.doi.org/10.1021/cb800039y

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OCA

[1] Xie P, Williams DS, Atilla-Gokcumen GE, Milk L, Xiao M, Smalley KS, Herlyn M, Meggers E, Marmorstein R. Structure-based design of an organoruthenium phosphatidyl-inositol-3-kinase inhibitor reveals a switch governing lipid kinase potency and selectivity. ACS Chem Biol. 2008 May 16;3(5):305-16. PMID:18484710 doi:http://dx.doi.org/10.1021/cb800039y

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