Template:STRUCTURE 2zm3

File:2zm3.png

Complex Structure of Insulin-like Growth Factor Receptor and Isoquinolinedione InhibitorComplex Structure of Insulin-like Growth Factor Receptor and Isoquinolinedione Inhibitor

Template:ABSTRACT PUBMED 18501599

DiseaseDisease

Known disease associated with this structure: Intrauterine and postnatal growth retardation OMIM:[147370]

About this StructureAbout this Structure

2ZM3 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

Lead identification to generate isoquinolinedione inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment., Mayer SC, Banker AL, Boschelli F, Di L, Johnson M, Kenny CH, Krishnamurthy G, Kutterer K, Moy F, Petusky S, Ravi M, Tkach D, Tsou HR, Xu W, Bioorg Med Chem Lett. 2008 Jun 15;18(12):3641-5. Epub 2008 Apr 25. PMID:18501599

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