2pr3

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Template:STRUCTURE 2pr3

File:2pr3.png

Factor XA inhibitorFactor XA inhibitor

Template:ABSTRACT PUBMED 17581239

DiseaseDisease

Known disease associated with this structure: Factor X deficiency OMIM:[227600]

About this StructureAbout this Structure

2PR3 is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

Structure-based drug design of pyrrolidine-1, 2-dicarboxamides as a novel series of orally bioavailable factor Xa inhibitors., Van Huis CA, Bigge CF, Casimiro-Garcia A, Cody WL, Dudley DA, Filipski KJ, Heemstra RJ, Kohrt JT, Narasimhan LS, Schaum RP, Zhang E, Bryant JW, Haarer S, Janiczek N, Leadley RJ Jr, McClanahan T, Thomas Peterson J, Welch KM, Edmunds JJ, Chem Biol Drug Des. 2007 Jun;69(6):444-50. PMID:17581239

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