2ozr
MMP13 Catalytic Domain Complexed with 4-{[1-methyl-2,4-dioxo-6-(3-phenylprop-1-yn-1-yl)-1,4-dihydroquinazolin-3(2H)-yl]methyl}benzoic acid
Template:ABSTRACT PUBMED 17623656
About this StructureAbout this Structure
2OZR is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
Discovery and characterization of a novel inhibitor of matrix metalloprotease-13 that reduces cartilage damage in vivo without joint fibroplasia side effects., Johnson AR, Pavlovsky AG, Ortwine DF, Prior F, Man CF, Bornemeier DA, Banotai CA, Mueller WT, McConnell P, Yan C, Baragi V, Lesch C, Roark WH, Wilson M, Datta K, Guzman R, Han HK, Dyer RD, J Biol Chem. 2007 Sep 21;282(38):27781-91. Epub 2007 Jul 10. PMID:17623656
Page seeded by OCA on Mon Jul 28 13:40:44 2008
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OCACategories:
- Pages with broken file links
- Homo sapiens
- Single protein
- Banotai, C A.
- Baragi, V.
- Bornemeier, D A.
- Datta, K.
- Dyer, R D.
- Fasquelle, V.
- Guzman, R.
- Han, H K.
- Johnson, A R.
- Lesch, C.
- Lie, J J.
- Man, C F.
- McConnell, P.
- Mueller, W T.
- Ortwine, D F.
- Pavlovsky, A G.
- Prior, F.
- Roark, W H.
- Robertson, D.
- Wilson, M.
- Yan, C H.
- Crystal complex structure
- Hydrolase
- Matrix metalloproteinase
- Mmp13 catalytic domain
- Mmp13 specific inhibitor