2j4z

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Template:STRUCTURE 2j4z

File:2j4z.png

STRUCTURE OF AURORA-2 IN COMPLEX WITH PHA-680626STRUCTURE OF AURORA-2 IN COMPLEX WITH PHA-680626

Template:ABSTRACT PUBMED 17125279

About this StructureAbout this Structure

2J4Z is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles: identification of a potent Aurora kinase inhibitor with a favorable antitumor kinase inhibition profile., Fancelli D, Moll J, Varasi M, Bravo R, Artico R, Berta D, Bindi S, Cameron A, Candiani I, Cappella P, Carpinelli P, Croci W, Forte B, Giorgini ML, Klapwijk J, Marsiglio A, Pesenti E, Rocchetti M, Roletto F, Severino D, Soncini C, Storici P, Tonani R, Zugnoni P, Vianello P, J Med Chem. 2006 Nov 30;49(24):7247-51. PMID:17125279

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