2fz8

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Template:STRUCTURE 2fz8

File:2fz8.png

Human Aldose reductase complexed with inhibitor zopolrestat at 1.48 A(1 day soaking).Human Aldose reductase complexed with inhibitor zopolrestat at 1.48 A(1 day soaking).

Template:ABSTRACT PUBMED 16952371

About this StructureAbout this Structure

2FZ8 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

Expect the unexpected or caveat for drug designers: multiple structure determinations using aldose reductase crystals treated under varying soaking and co-crystallisation conditions., Steuber H, Zentgraf M, Gerlach C, Sotriffer CA, Heine A, Klebe G, J Mol Biol. 2006 Oct 13;363(1):174-87. Epub 2006 Aug 9. PMID:16952371

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