1pwm

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Template:STRUCTURE 1pwm

File:1pwm.png

Crystal structure of human Aldose Reductase complexed with NADP and FidarestatCrystal structure of human Aldose Reductase complexed with NADP and Fidarestat

Template:ABSTRACT PUBMED 15146479

About this StructureAbout this Structure

1PWM is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with Fidarestat and Minalrestat: implications for the binding of cyclic imide inhibitors., El-Kabbani O, Darmanin C, Schneider TR, Hazemann I, Ruiz F, Oka M, Joachimiak A, Schulze-Briese C, Tomizaki T, Mitschler A, Podjarny A, Proteins. 2004 Jun 1;55(4):805-13. PMID:15146479

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