1sn4
STRUCTURE OF SCORPION NEUROTOXIN BMK M4STRUCTURE OF SCORPION NEUROTOXIN BMK M4
Structural highlights
FunctionSCX4_MESMA Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission. This toxin is active against mammals. Evolutionary ConservationCheck, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. |
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