1nce

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File:1nce.png

Template:STRUCTURE 1nce

Crystal structure of a ternary complex of E. coli thymidylate synthase D169C with dUMP and the antifolate CB3717Crystal structure of a ternary complex of E. coli thymidylate synthase D169C with dUMP and the antifolate CB3717

Template:ABSTRACT PUBMED 12702803

About this StructureAbout this Structure

1NCE is a Single protein structure of sequence from Escherichia coli, and escherichia coli o157:h7. Full crystallographic information is available from OCA.

ReferenceReference

The only active mutant of thymidylate synthase D169, a residue far from the site of methyl transfer, demonstrates the exquisite nature of enzyme specificity., Birdsall DL, Finer-Moore J, Stroud RM, Protein Eng. 2003 Mar;16(3):229-40. PMID:12702803

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