1c9f

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NMR STRUCTURE OF THE CAD DOMAIN OF CASPASE-ACTIVATED DNASENMR STRUCTURE OF THE CAD DOMAIN OF CASPASE-ACTIVATED DNASE

Structural highlights

1c9f is a 1 chain structure with sequence from Mus musculus. The August 2004 RCSB PDB Molecule of the Month feature on Caspases by David S. Goodsell is 10.2210/rcsb_pdb/mom_2004_8. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

DFFB_MOUSE Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

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OCA